Wednesday, September 16, 2009

Patients Prescribed Tramadol Less Likely To Develop Dependency

Most people live their lives taking their health for granted, as long as they are feeling no pain. But if they happen to suffer a physical injury, the first thing on their mind is finding a way to reduce the pain. Tramadol is one of the most widely used pain relief medicines available to patients who are in need of treatment for moderate to severe pain. It is an analgesic, or pain killer that works on the brain and nervous systems in somewhat mysterious ways. While it is classified as an opioid, it is very much unlike any other pain relief medicine in this classification such as morhine and codeine. It is not considered to be a controlled substance in the United States, which means that it can be obtained with a standard prescription from any medical doctor. Patients can even buy Tramadol at an online pharmacy via one of the many US licensed pharmacies on the Internet.

A German pharmaceutical company named Grunenthal GmbH invented Tramadol in their laboratory near the end of the 1970s. At that time they gave it the name Tramal. Since then they have sold the rights to a wide variety of companies around the world who have come up with a lot of different names. A company in Argentina markets it as Calmador. In Sweden a company sells it as Tradolan. In Isreal it is sold as Tramadex, and in South Korea this particular medicine can be purchased as Tandol. Ultram and Ultracet are other names for this prescription drug in the United States. Today there are over 55 different brand names for Tramadol worldwide.

There is releatively little negative health related press attached to Tramadol as a prescription medicine, mostly because it is not abused recreationally as much as some other opioids. The reported negative side effects of Tramadol abuse are nausea, abnormal sweating, vomiting, constipation and seizures. These side effects can create a very unpleasant experience if this drug is abused, which puts it low on the lists of prescription drugs for experimental drug users.

Tramadol is available by a prescription from US licensed physicians and legal to be purchased online at US licensed pharmacies or at any pharmacy. This is due to the fact that this synthetic agent is less likely to cause a dependency if used for an extended period of time. This is an important factor when doctors consider the long term health of their patients who take a prescribed Medicine for pain.

Unlike other prescription drugs in its class, Tramadol has a relatively mild effect on the mu opioid receptor. This is a nerve receptor that is located in the periaqueductal grey area of the brain, otherwise known as the midbrain grey matter area. It is responsible for what is called the Gate Control Theory of pain relief. Opioids such as morphine and vicodin bind very easily to it and inhibit the pathway of the neurons that are being sent to the brain to register pain. The Gate Control Theory is the basis of most modern analgesics and it has revolutionized the way pain can be managed.

This affinity to the mu opioid receptor can also be responsible for the creation of a dependency to the opioid drug that is being used. However, Tramadol has a weaker affinity to this receptor than the other opioids in its class, which means that addiction is less likely to occur. Thus, the health of the patient is compromised less by taking this particular medicine to reduce their pain.

Tramadol can be taken in many different forms including orally in a pill or tablet form, rectally with suppositories, injected and with an IV in hospitals. The dosages range from 50 to 400 milligrams per day, which is determined by the attending physician.

While it is true that the mild agonism of the mu opioid receptor is partially responsible for the effectiveness of Tramadol in treating pain, doctors and scientists are not quite sure about the other details of why Tramadol works. They know that it is something to do with the effect it has on the noradrenergic and serotonergic systems in the human body.

The serotonergic system involves the neurotransmitter known as serotonin which is responsible for many different functions in the human body. Among its many duties serotonin is in charge of the regulation of various moods such as anger, as well as the regulation of sleeping patterns and appetite. It is created in the intestines by the amino acid tryptophan.

The noradrenergic system is responsible for such things as the fight or flight response we get when we are placed in a very stressful and dangerous situation. When a situation like this happens, norepinephrine which is also know as noradrenaline is sent to the part of the brain that controls attention and response processing. This hormone and neurotransmitter comes from a gland located in a part of the brain stem called the locus ceruleous. A neurotransmitter system is activated that sends neurons instantly along the spinal cord and distributes them to all parts of the body through millions of nerve pathways.

When norepinephrine is triggered the subjects heart rate increases, glucose is released into the bloodstream from stored up energy and all the muscles of the skeletin experience an increase in blood flow. The subject also experiences increased alertness and arousal. Studies have shown that the effect Tramadol has on the noradrenergic system may also have something to do with the decreased risk of developing a dependency, although the reason why is still not known.

Treating and controlling pain has come a long way in the past 100 years. The discovery of opioid based prescription drugs like morhine, codeine and vicodin have revolutionized pain treatment and brought relief to millions around the world who suffer from moderate to severe pain. However, there has been a negative health side effect from this benefit and it is the creation of dependencies on these drugs for millions of patients who took their prescribed pain medicine for extended periods of time.

Tramadol is a synthetic opioid medicine and it may be in the same class as the natural opiate based prescription drugs morphine and vicodin, but it has two very big differences from these two medicines. For one, it is not considered to be a controlled substance in the United States. This means that US licensed physicians can prescribe this analgesic to patients who can buy it at any pharmacy or online pharmacy that happens to be one of the many US licensed pharmacies on the Internet.

But the biggest thing that makes Tramadol different than other prescription drug opioids is that it can alleviate pain with a much lower chance of causing an addiction to the drug. This is very important when you consider the long term health of people who take pain medicine for extended periods of time.

Want to Get Relief of Chronic Pain

Most of us suffer from severe or moderate pain in our life and many people wants to get relief with pain relief medicine and other medications. It is also a truth that most of us may not be forgetting the moments when we fall from the roof, slip in bathroom or got a bee sting or the pain occurred during the birth of a child.

Many people across the world go through from different sort of pain such as chronic pain, acute, back pain, severe pain, muscle pain and other types of pains. Every one may have realized pain in one form or the other. Sometimes you face back pain or migraine after a whole day of laborious work; others may be having muscle pain or joint pains due to arthritis or pain due to undergoing surgery.

Most of the times, these types of pain become a part of every one's daily life and health largely. It hinders the development and living of a person so it becomes necessary to get relief from these types of pains. Most of the approved medicines give relief from daily life pain whether acute or severe.

Generally all the people may be experience these types of pain and is accompanied with trauma, to a certain part of the body. There are mainly three medicines available in the store and online pharmacy which is approved by FDA. They are as follows-:

1. Ultram - Ultram is the brand name for tramadol hat is being used as a pain reliever for moderate to severe pain caused after any surgery or other types of pain. Now you can Buy ULTRAM Online with no prescription.

2. Butalbital - Butalbital belongs to the group of medicines known as Barbiturates and has a composition that relieves pain and acts as a relaxant. It is commonly used for the treatment of migraine headaches.

3. Ultracet - Ultracet is the brand name for the combination of two drugs, tramadol (Ultram) and acetaminophen (Tylenol). It is an analgesic used for patients to relieve them of any sort of acute, moderate, or severe pain caused by any surgery or other types of pain.

Take proper instructions about your diet when you take the drugs. Do not leave behind any confusion in your mind and get clear all your doubts. Let the doctor know, how intelligent his patient is.

If you face any sort of problem with the dosage or if you had any problem with the prescribed drug in the past, it is your duty to bring it to the knowledge of the doctor. You are helping your cause by informing him everything about you.

Tuesday, September 15, 2009

Pain Medication You Can Legally Order Online

Millions of American live with pain. Chronic pain, daily pain, short term severe pain. Of all the medications sold by online pharmacies, by far the most common type is pain relievers. You might think then that online pharmacies are a great source of pain relievers.

Well, did you know the Drug Enforcement Agency of the United States (DEA) has busted and close over 5000 online pharmacies? Did you know that many online pharmacies sell counterfeit medication? Did you know it is a federal crime for you to order prescription drugs from outside the United States?

It is true, online pharmacies are a great source of pain relief medication. This article teaches you to order pain medication legally, from within the United States, with a legal prescription. It’s the only way to go!

First, the caveats: You cannot legally order medication from outside the United States, even if you have a prescription. We always hear about the elderly taking buses to Canada to buy cheap medicine. The fact is, as of this writing, this course is illegal. Also, you cannot legally order medicine from a pharmacy without a prescription. Many online pharmacies (including my own) have physicians on staff who review your medication request and write you a prescription if they think it’s safe. In addition, NEVER order narcotics through the mail. Forget codeine, Tylenol #3, oxycontin, demerol, percodan and percocet. You can be charged with a federal crime for buying these substances. Lastly, regardless of the medication you buy, be sure to read the package insert (or a monograph on my web site). Drugs interact with each other and with your body- the package insert will tip you off to potentially dangerous behavior with respect to the medication you ordered.

The following are quick summaries of common pain relief drugs you can order through the Internet with very little risk:

Fioricet (butalbital)

Fioricet is a combination drug. It is made up of acetaminophen, caffeine and butalbital. Acetaminophen is the same medication in Tylenol You know caffeine from coffee (or even your favorite candy bar.) Butalbital is a mild barbiturate. It relaxes you.

Medical Science does not have an explanation for the reason this combination of drugs works so well, but the fact is Fioricet (and its generic form butalbital) is highly effective for tension headache. Presumably, it relaxes the muscles in the head and neck which typically tighten during tension headaches.. This is the top selling drug at our pharmacy month after month- it really helps headaches!

Soma (carisoprodol)

Soma is a muscle relaxant. It acts by blocking electrical signals among nerves in the reticular formation of the brain and in the spinal cord. Carisoprodol, combined with rest and physical therapy, is prescribed for the short term relief of painful muscle conditions- particularly muscle spasm (where the muscle tightens and does not relax). Most back strains result in muscle spasm, so patients find carisoprodol highly effective in relieving back pain.

Celebrex (celecoxib)

Celebrex is used in the treatment of symptoms of arthritis. This includes joint pain, stiffness, swelling and inflammation. The medication does not cure arthritis, but does provide symptomatic relief. It s a nonsteroidal anti-inflammatory drug (NSAID) which relieves pain and inflammation. The drug works by blocking the production of prostaglandins in the body. Prostaglandins contribute to the pain and swelling associated with arthritis.

Ultram (tramadol)

Ultram is used for treatment of moderate to severe chronic pain. It binds to the opiod receptors on nerves (the same mechanism used by narcotics), but it has a far lower potential for dependency. It’s the closest medication to a narcotic you can order legally in the US online. It is not a NSAID (nonsteroidal anti- inflammatory drug) and does not carry the risk of stomach ulceration and internal bleeding which can accompany the use of such medications. It is often prescribed for pain associated with shingles, fibromyalgia and other chronic diseases.

Ulracet

Ultracet is a combination of acetaminophen and tramadol. It is typically prescribed for the short term (up to five days) relief of moderately severe acute pain. It is often prescribed for post-surgical pain or after dental procedures.

The ultram mechanism as described above is very similar to the mechanism employed by narcotics. Acetaminophen of course is the active ingredient in Tylenol. It works by increasing the threshold to pain (i.e. it takes more pain stimulus to cause the sensation of pain). These two drugs work by different mechanisms, and they combine to be more effective than either drug alone.

Pain relief medication can be ordered safely online, but one should exercise appropriate caution before doing so. Specifically, it’s important to determine whether you need to see a physician before ordering pain medication. If you have a sudden onset of pain which is not readily explained, you should consult a physician first. If in doubt, go to the emergency room. If however you are a patient who has been diagnosed, and pain is a recurring problem, you can conveniently order pain medication online- typically at a lower cost than the combined cost of a doctor’s appointment and the medication itself.

UltraCET: The Dynamic Duo Of Prescription Pain Control Medications

Remember the last time you stubbed your toe? OUCH! It’s painful. But a stubbed toe usually doesn’t send us running to the Medicine cabinet, since we know that the pain will pass within a few minutes.

But for more serious “acute” pain (pain that’s severe and constant for a couple of days), waiting it out may not be an option. For some acute pain, we might even make things worse: for example, if you hold a painful joint at an awkward angle to relieve the pain, you might end up with a muscle strain.

So what are our options? Sometimes simple over the counter medications may do the trick. But for when they don’t, a prescription medication may be the best bet.

UltraCET: Two Tough Drugs in one Small Pill

For acute pain from sprains, muscle strains, surgery, or dental work, or for arthritis flare-ups, UltraCET is a terrific option.

UltraCET is like any heroic dynamic duo (think Batman and Robin, or Xena and Gabrielle): One drug has the high-profile effect, but the other has an equally important, though less noticeable set of activities.

The “ultra” part of UltraCET is tramadol, the generic name for Ultram. Tramadol’s effect on your body is similar to the effect of narcotics (drugs like opium and heroin which are illegal, and codeine and morphine, which aren’t). Tramadol is just as good as narcotics in relieving pain but because unlike narcotics, it doesn’t affect your breathing or have other side-effects which stop us from regularly using medical narcotics.

The “CET” part of UltraCET is probably familiar to you in its day-to-day formulation; you might even have it in your medicine cabinet! It’s acetaminophen, the same drug that’s in Tylenol.

The two drugs work together (in “synergy”) to control pain. Acetaminophen helps “increase your threshold to pain.” That’s a fancy way of saying that mild pain signals from your body don’t even make it up to your brain so they don’t register. The bigger pain signals do make it to your brain, but that’s where tramadol kicks in - stopping the pain signals while they’re working their way through your brain. It’s just like Robin capturing the villain’s henchmen while Batman tackles the mastermind villain!

This Sounds Like The Perfect Rescue!

If you’ve just been seen by a doctor (a surgeon, or a dentist), she may well have already prescribed UltraCET for you. If you haven’t, but you’ve got a sprain or regular arthritis flares, you should talk with your doctor about a prescription for this drug.

Like anything powerful, though, you need to use it at the right time for the right reasons (letting Xena show off her acrobatic skills in a china shop is not a terrific idea!). The most important thing about taking UltraCET is to remember that it’s for short term use only!

Most doctors will suggest using it for up to five days only because you can otherwise become dependent on (addicted to) it. Stopping the drug after taking it a long time can cause severe withdrawal symptoms, so never take more than the doctor prescribes.

Your doctor will also ask you about other drugs that you’re taking. Tylenol, some antidepressants, and some seizure medications don’t mix with UltraCET. Neither does drinking, so you might wait to celebrate until after your sprain has healed!

Once these issues are resolved, your doctor can send you home with a prescription for UltraCET. It’ll help you get through the worst of the pain, and then best of all, it can ride off into the sunset when its job is done, leaving you to your pain-free life!

Copyright (C) Shoppe.MD and Ian Mason, 2004-2005

Ian Mason, owner of Shoppe.MD, the only online pharmacy with pain support forums and UltraCET medication.

Ian is a fat-to-fit student of health, weight loss, exercise, and several martial arts; maintaining several websites in an effort to help provide up-to-date and helpful information for other who share his interests in health of body and mind.